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A uterotonic is an agent used to induce contraction or greater tonicity of the uterus. Utertonics are used both to induce labor, and to reduce postpartum hemorrhage. Some uterotonics act as analogues of oxytocin. An oxytocinergic, or oxytocic, means "having to do with oxytocin (OXT)". The Oxytocin Receptor (OXTR) is the binding and activation site of oxytocin. Some agents may act as indirect oxytocinergics: 5-HT1A Receptor (5-HT1AR): A protein responsible for inducing the secretion of oxytocin. Serotonergic: A drug which acts upon serotonin and 5-HT1AR, resulting in oxytocin release (e.g., MDMA ("Ecstasy"). Other uterotonics include Methylergonovine and Prostaglandin F2. A tocolytic acts to oppose uterine contractility. These agents may be oxytocinergic in mechanism. For example, Atosiban works in this way. See also Look up Oxytocinergic in Wiktionary, the free dictionary. Atosiban Carbetocin Demoxytocin L-371,257 Oxytocin WAY-267,464 References This article does not cite any references or sources. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. (August 2009) v • d • e Anxiolytics (N05B) GABAA PAMs Benzodiazepine Adinazolam • Alprazolam • Bretazenil • Bromazepam • Camazepam • Chlordiazepoxide • Clobazam • Clonazepam • Clorazepate • Clotiazepam • Cloxazolam • Diazepam • Ethyl Loflazepate • Etizolam • Fludiazepam • Halazepam • Imidazenil • Ketazolam • Lorazepam • Medazepam • Nordazepam • Oxazepam • Pinazepam • Prazepam Carbamates Emylcamate • Mebutamate • Meprobamate (Carisoprodol, Tybamate) • Phenprobamate • Procymate Nonbenzodiazepines Abecarnil • Adipiplon • Alpidem • CGS-9896 • CGS-20625 • Divaplon • ELB-139 • Fasiplon • GBLD-345 • Gedocarnil • L-838,417 • NS-2664 • NS-2710 • Ocinaplon • Pagoclone • Panadiplon • Pipequaline • RWJ-51204 • SB-205,384 • SL-651,498 • Taniplon • TP-003 • TP-13 • TPA-023 • Y-23684 • ZK-93423 Pyrazolopyridines Cartazolate • Etazolate • ICI-190,622 • Tracazolate Others Chlormezanone • Ethanol (Alcohol) • Etifoxine • Kavalactones (Kava Kava) • Skullcap • Valerenic Acid (Valerian) α2δ VDCC Blockers Gabapentin • Pregabalin 5-HT1A Agonists Azapirones: Buspirone • Gepirone • Tandospirone; Others: Flesinoxan • Oxaflozane H1 Antagonists Diphenylmethanes: Captodiame • Hydroxyzine; Others: Brompheniramine • Chlorpheniramine • Pheniramine CRH1 Antagonists Antalarmin • CP-154,526 • Pexacerfont • Pivagabine NK2 Antagonists GR-159,897 • Saredutant MCH1 antagonists ATC-0175 • SNAP-94847 mGluR2/3 Agonists Eglumegad mGluR5 NAMs Fenobam TSPO agonists DAA-1097 • DAA-1106 • Emapunil • FGIN-127 • FGIN-143 σ1 agonists Afobazole • Opipramol Others Benzoctamine • Carbetocin • Demoxytocin • Mephenoxalone • Mepiprazole • Oxanamide • Oxytocin • Promoxolane • Tofisopam • Trimetozine • WAY-267,464 #WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III M: PSO/PSI mepr dsrd (o, p, m, p, a, d, s), sysi/epon, spvo proc, drug(N5A/5B/5C/6A/6B/6D) v • d • e Uterotonics/labor inducers/oxytocics (G02A) Cervical ripening Ergot alkaloids Ergometrine# (Syntometrine) · Methylergometrine Prostaglandins and analogues E: Misoprostol/E1# · Gemeprost/E1 · Dinoprostone/E2 · Sulprostone/E2 F: Dinoprost/F2α · Carboprost/F2α Contraction induction Oxytocin# · Carbetocin · Demoxytocin · WAY-267,464 #WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III M: OBS phys/devp mthr/fetu/infc, epon proc, drug(2A/G2C) v • d • e Neuropeptidergics Cholecystokinin CCKA Agonists: Cholecystokinin • CCK-4 Antagonists: Asperlicin • Proglumide • Lorglumide • Devazepide • Dexloxiglumide CCKB Agonists: Cholecystokinin • CCK-4 • Gastrin Antagonists: Proglumide • CI-988 CRH CRF1 Agonists: Corticotropin releasing hormone Antagonists: Antalarmin • CP-154,526 • Pexacerfont CRF2 Agonists: Corticotropin releasing hormone Galanin GAL1 Agonists: Galanin • Galanin-like peptide • Galmic • Galnon GAL2 Agonists: Galanin • Galanin-like peptide • Galmic • Galnon GAL3 Agonists: Galanin • Galmic • Galnon Ghrelin Agonists: Ghrelin • Capromorelin • MK-677 • Sermorelin • SM-130,686 • Tabimorelin MCH MCH1 Agonists: Melanin concentrating hormone Antagonists: ATC-0175 • GW-803,430 • NGD-4715 • SNAP-7941 • SNAP-94847 MCH2 Agonists: Melanin concentrating hormone Melanocortin MC1 Agonists: alpha-MSH • Afamelanotide • Bremelanotide • Melanotan II Antagonists: Agouti signalling peptide MC2 Agonists: ACTH • Cosyntropin • Tetracosactide MC3 Agonists: alpha-MSH • Bremelanotide • Melanotan II MC4 Agonists: alpha-MSH • Bremelanotide • Melanotan II • THIQ Antagonists: Agouti-related peptide MC5 Agonists: alpha-MSH • Melanotan II Neuropeptide S Agonists: Neuropeptide S Antagonists: SHA-68 Neuropeptide Y Y1 Agonists: Neuropeptide Y • Peptide YY Antagonists: BIBP-3226 Y2 Agonists: Neuropeptide Y • Peptide YY Antagonists: BIIE-0246 Y4 Agonists: Neuropeptide Y • Pancreatic polypeptide • Peptide YY Antagonists: UR-AK49 Y5 Agonists: Neuropeptide Y • Peptide YY Antagonists: Lu AA-33810 Neurotensin NTS1 Agonists: Neurotensin • Neuromedin N Antagonists: SR-48692 • SR-142,948 NTS2 Agonists: Neurotensin Antagonists: Levocabastine • SR-142,948 Opioid see Template:Opioids Orexin OX1 Agonists: Orexin-A Antagonists: Almorexant • SB-334,867 • SB-408,124 • SB-649,868 OX2 Agonists: Orexin-A Antagonists: Almorexant • SB-649,868 • TCS-OX2-29 Oxytocin Agonists: Carbetocin • Demoxytocin • Oxytocin • WAY-267,464 Antagonists: Atosiban • L-371,257 Tachykinin NK1 Agonists: Substance P Antagonists: Aprepitant • Befetupitant • Casopitant • CI-1021 • CP-96,345 • CP-99,994 • CP-122,721 • Dapitant • Ezlopitant • FK-888 • Fosaprepitant • GR-203,040 • GW-597,599 • HSP-117 • L-733,060 • L-741,671 • L-743,310 • L-758,298 • Lanepitant • LY-306,740 • Maropitant • Netupitant • NKP-608 • Nolpitantium • Orvepitant • RP-67,580 • SDZ NKT 343 • Vestipitant • Vofopitant NK2 Agonists: Neurokinin A Antagonists: GR-159,897 • Ibodutant • Saredutant NK3 Agonists: Neurokinin B Antagonists: Osanetant • Talnetant Vasopressin V1A Agonists: Desmopressin • Felypressin • Ornipressin • Terlipressin • Vasopressin Antagonists: Conivaptan • Demeclocycline • Relcovaptan V1B Agonists: Felypressin • Ornipressin • Terlipressin • Vasopressin Antagonists: Demeclocycline • Nelivaptan V2 Agonists: Desmopressin • Ornipressin • Vasopressin Antagonists: Conivaptan • Demeclocycline • Lixivaptan • Mozavaptan • Satavaptan • Tolvaptan This article has not been added to any categories. Please help out by adding categories to it so that it can be listed with similar articles, in addition to a stub category. Please remove this tag after categorizing. (September 2010) This biology article is a stub. You can help Wikipedia by expanding it. v • d • e