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This article is an orphan, as few or no other articles link to it. Please introduce links to this page from related articles; suggestions may be available. (February 2009) edit Ciliary rootlet coiled-coil, rootletin Identifiers Symbols CROCC; KIAA0445 External IDs MGI: 3529431 HomoloGene: 16811 GeneCards: CROCC Gene Gene Ontology Molecular function • structural molecule activity • kinesin binding Cellular component • centriole • ciliary rootlet Biological process • cell cycle • centrosome organization and biogenesis Orthologs Species Human Mouse Entrez 9696 230872 Ensembl n/a ENSMUSG00000040860 UniProt n/a Q99PL9 RefSeq (mRNA) NM_014675 NM_172122 RefSeq (protein) NP_055490 NP_742120 Location (UCSC) n/a Chr 4: 140.29 - 140.33 Mb PubMed search [1] [2] Rootletin is a protein that in humans is encoded by the CROCC gene.[1][2][3] References ^ Yang J, Liu X, Yue G, Adamian M, Bulgakov O, Li T (Nov 2002). "Rootletin, a novel coiled-coil protein, is a structural component of the ciliary rootlet". J Cell Biol 159 (3): 431–40. doi:10.1083/jcb.200207153. PMC 2173070. PMID 12427867.  ^ McClintock TS, Glasser CE, Bose SC, Bergman DA (Jan 2008). "Tissue expression patterns identify mouse cilia genes". Physiol Genomics 32 (2): 198–206. doi:10.1152/physiolgenomics.00128.2007. PMID 17971504.  ^ "Entrez Gene: CROCC ciliary rootlet coiled-coil, rootletin".  Further reading Ching YP, Chan SF, Jeang KT, Jin DY (2006). "The retroviral oncoprotein Tax targets the coiled-coil centrosomal protein TAX1BP2 to induce centrosome overduplication.". Nat. Cell Biol. 8 (7): 717–24. doi:10.1038/ncb1432. PMID 16767081.  Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.  Bahe S, Stierhof YD, Wilkinson CJ, et al. (2005). "Rootletin forms centriole-associated filaments and functions in centrosome cohesion.". J. Cell Biol. 171 (1): 27–33. doi:10.1083/jcb.200504107. PMC 2171225. PMID 16203858.  Andersen JS, Wilkinson CJ, Mayor T, et al. (2003). "Proteomic characterization of the human centrosome by protein correlation profiling.". Nature 426 (6966): 570–4. doi:10.1038/nature02166. PMID 14654843.  Behrends U, Schneider I, Rössler S, et al. (2003). "Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries.". Int. J. Cancer 106 (2): 244–51. doi:10.1002/ijc.11208. PMID 12800201.  Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.  Seki N, Ohira M, Nagase T, et al. (1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.". DNA Res. 4 (5): 345–9. doi:10.1093/dnares/4.5.345. PMID 9455484.  This protein-related article is a stub. You can help Wikipedia by expanding it.v · d · e