Your IP: 18.234.244.170 United States Near: Cambridge, Massachusetts, United States

Lookup IP Information

Previous 1 2 3 4 5 6 7 8 Next

Below is the list of all allocated IP address in 178.252.0.0 - 178.252.255.255 network range, sorted by latency.

This article is an orphan, as few or no other articles link to it. Please introduce links to this page from related articles; suggestions may be available. (February 2009) edit CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) Identifiers Symbols CDIPT; MGC1328; PIS; PIS1 External IDs OMIM: 605893 MGI: 105491 HomoloGene: 7159 GeneCards: CDIPT Gene Gene Ontology Molecular function • magnesium ion binding • CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity • phosphatidylinositol transporter activity • transferase activity • manganese ion binding Cellular component • endoplasmic reticulum • membrane • integral to membrane Biological process • phospholipid biosynthetic process Sources: Amigo / QuickGO RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 10423 52858 Ensembl ENSG00000103502 ENSMUSG00000030682 UniProt O14735 Q05BY1 RefSeq (mRNA) NM_145752 NM_026638 RefSeq (protein) NP_665695 NP_080914 Location (UCSC) Chr 16: 29.78 - 29.78 Mb Chr 7: 126.77 - 126.77 Mb PubMed search [1] [2] CDP-diacylglycerol--inositol 3-phosphatidyltransferase is an enzyme that in humans is encoded by the CDIPT gene.[1][2] Phosphatidylinositol breakdown products are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. Two enzymes, CDP-diacylglycerol synthase and phosphatidylinositol synthase, are involved in the biosynthesis of phosphatidylinositol. Phosphatidylinositol synthase, a member of the CDP-alcohol phosphatidyl transferase class-I family, is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus.[2] References ^ Lykidis A, Jackson PD, Rock CO, Jackowski S (Jan 1998). "The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content". J Biol Chem 272 (52): 33402–9. doi:10.1074/jbc.272.52.33402. PMID 9407135.  ^ a b "Entrez Gene: CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10423.  Further reading Antonsson B (1997). "Phosphatidylinositol synthase from mammalian tissues.". Biochim. Biophys. Acta 1348 (1-2): 179–86. PMID 9370331.  Antonsson BE (1994). "Purification and characterization of phosphatidylinositol synthase from human placenta.". Biochem. J. 297 ( Pt 3): 517–22. PMC 1137864. PMID 8110188.  Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.  Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.  Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.  Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216.  Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.  de Serres FJ, Luisetti M, Ferrarotti I, et al. (2005). "Alpha-1 antitrypsin deficiency in Italy: regional differences of the PIS and PIZ deficiency alleles.". Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo 63 (3): 133–41. PMID 16312203.  This article on a gene on chromosome 16 is a stub. You can help Wikipedia by expanding it.v · d · e