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This article needs additional citations for verification. Please help improve this article by adding reliable references. Unsourced material may be challenged and removed. (December 2008) This article includes a list of references, related reading or external links, but its sources remain unclear because it lacks inline citations. Please improve this article by introducing more precise citations where appropriate. (December 2008) Image of a Nissl-stained histological section through the rodent hippocampus showing various classes of neurons. Motor nerve cell from ventral horn of medulla spinalis of rabbit. The angular and spindle-shaped Nissl bodies are well shown. A Nissl body (or Nissl granule or tigroid body) is a large granular body found in neurons. These granules are rough endoplasmic reticulum (with free ribosomes) and are the site of protein synthesis. It was named after Franz Nissl, German neurologist (1860-1919)[1]. Nissl bodies can be demonstrated by a method of selective staining developed by Nissl (Nissl staining), using an aniline stain to label extranuclear RNA granules. This staining method is useful to localize the perikaryon, cell body, as it can be seen in the Soma (biology) and dendrites of neurons, though not in the axon or axon hillock. RNA stains blue with this method due to its basophilic (lat. "base-loving") properties. Nissl bodies show changes under various physiological conditions and in pathological conditions they may dissolve and disappear (karyolysis). They are thought to be involved in the synthesis of neurotransmitters such as acetylcholine. See also Franz Nissl External links MeSH Nissl+Bodies Histology at BU 04103loa - "Nervous Tissue and Neuromuscular Junction: spinal cord, cell bodies of anterior horn cells" Anatomy at MUN nerve/nerve97 (halfway down page) Histology at anhb.uwa.edu.au Tissues containing Nissl bodies at harvard.edu References ^ [synd/2902 at Who Named It? "Nissl's substance"]. synd/2902 at Who Named It?. Retrieved 2009-02-25.  v • d • e Histology: nervous tissue (TA A14.2.00, GA 9.849) Neurons Parts soma axon (axon hillock, axon terminals, axoplasm, axolemma, neurofibril/neurofilament) dendrite (Nissl body, dendritic spine, apical dendrite, basal dendrite) Types bipolar · pseudounipolar · multipolar · pyramidal · Purkinje · granule Afferent nerve fiber/ Sensory nerve GSA · GVA · SSA · SVA fibers (Ia, Ib or Golgi, II or Aβ, III or Aδ or fast pain, IV or C or slow pain) Efferent nerve fiber/ Motor nerve GSE · GVE · SVE Upper motor neuron · Lower motor neuron (α motorneuron, γ motorneuron, β motorneuron) Termination Synapses neuropil · synaptic vesicle Interneuron (Renshaw) · neuromuscular junction · electrical synapse Sensory receptors Meissner's corpuscle · Merkel nerve ending · Pacinian corpuscle · Ruffini ending · Muscle spindle · Free nerve ending · Olfactory receptor neuron · Photoreceptor cell · Hair cell · Taste bud Support Glial cells Astrocyte (Radial glia) · Oligodendrocyte · Ependymal cells (Tanycytes) · Microglia Myelination CNS: Oligodendrocyte PNS: Schwann cell · Neurolemma · Nodes of Ranvier/Internode · Schmidt-Lanterman incisures Related connective tissues epineurium · perineurium · endoneurium · nerve fascicle · meninges Other Posterior (Root, Ganglion, Ramus) · Anterior (Root, Ramus) · rami communicantes (Gray, White) · Nerve fiber · Preganglionic fibers · Postganglionic fibers · Lemniscus · Funiculus · Fasciculus · Decussation · Commissure Projection fibers · Association fiber · Commissural fiber M: CNS anat(s,m,p,4,e,b,d,c,a,f,l,g)/phys/devp/cell noco(m,d,e,h,v,s)/cong/tumr,sysi/epon,injr proc,drug(N1A/2AB/C/3/4/7A/B/C/D) M: PNS anat(h,r,t,c,b,l,s)/phys/devp/prot/nttr/nttm/ntrp noco/auto/cong/tumr, sysi/epon, injr proc, drug(N1B) This neuroscience article is a stub. You can help Wikipedia by expanding it. v • d • e