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edit Olfactory receptor, family 12, subfamily D, member 2 Identifiers Symbols OR12D2; MGC126791; MGC126795; dJ994E9.8; hs6M1-20 External IDs MGI: 2177484 HomoloGene: 88379 GeneCards: OR12D2 Gene Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 26529 258831 Ensembl ENSG00000204690 ENSMUSG00000073398 UniProt n/a n/a RefSeq (mRNA) NM_013936 NM_146834 RefSeq (protein) NP_039224 NP_667045 Location (UCSC) Chr 6: 29.47 - 29.47 Mb Chr 17: 36.91 - 36.91 Mb PubMed search [1] [2] Olfactory receptor, family 12, subfamily D, member 2, also known as OR12D2, is a protein which in humans is encoded by the OR12D2 gene.[1] Contents 1 Function 2 References 3 Further reading 4 External links // Function Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1] References ^ a b "Entrez Gene: OR12D2 olfactory receptor, family 12, subfamily D, member 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26529.  Further reading Younger RM, Amadou C, Bethel G, et al. (2001). "Characterization of clustered MHC-linked olfactory receptor genes in human and mouse.". Genome Res. 11 (4): 519–30. doi:10.1101/gr.160301. PMID 11282967.  Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.  Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMID 14983052.  Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  External links MeSH OR12D2+protein,+human This article incorporates text from the United States National Library of Medicine, which is in the public domain. This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it. v • d • e v • d • e G protein-coupled receptors: olfactory receptors Class I (fish-like specific receptors) Family 51 A2 · A4 · A7 · B2 · B4 · B5 · B6 · D1 · E1 · E2 · F1 · F2 · G1 · G2 · H1 · I1 · I2 · L1 · M1 · Q1 · S1 · T1 · V1 Family 52 A1 · A4 · A5 · B2 · B4 · B6 · D1 · E1 · E2 · E4 · E5 · E6 · E8 · H1 · I1 · I2 · J3 · K1 · K2 · L1 · L2 · M1 · N1 · N2 · N4 · N5 · P1 · R1 · W1 Family 56 A1 · A3 · A4 · B1 · B4 Class II (tetrapod specific receptors) Family 1 A1 · A2 · B1 · C1 · D2 · D4 · D5 · E1 · E2 · F1 · F2 · G1 · I1 · J1 · J2 · J4 · K1 · L1 · L3 · L4 · L6 · L8 · M1 · N1 · N2 · Q1 · S1 · S2 Family 2 A1 · A2 · A4 · A5 · A7 · A12 · A14 · A25 · A42 · AE1 · AG1 · AG2 · AJ1 · AK2 · AP1 · AT4 · B2 · B3 · B6 · B8 · B11 · C1 · C3 · D2 · D3 · F1 · F2 · G2 · G3 · G6 · H1 · H2 · J1 · J2 · J3 · K2 · L2 · L3 · L5 · L8 · L13 · M2 · M3 · M4 · M5 · M7 · S2 · T1 · T2 · T3 · T4 · T5 · T6 · T8 · T10 · T11 · T12 · T27 · T29 · T33 · T34 · T35 · V1 · V2 · W1 · W3 · W5 · Y1 · Z1 Family 3 A1 · A2 · A3 · A4 Family 4 A5 · A15 · A16 · A47 · B1 · C3 · C5 · C6 · C11 · C12 · C13 · C15 · C16 · C45 · C46 · D1 · D2 · D5 · D6 · D9 · D10 · D11 · E2  · F3 · F4 · F5 · F6 · F15 · F16 · F17 · F21 · F29 · K1 · K2 · K3 · K5 · K13 · K14 · K15 · K17 · L1 · M1 · M2 · N2 · N4 · N5 · P4 · Q3 · S1 · S2 · X1 · X2 Family 5 A1 · A2 · AC2 · AK2 · AK3 · AN1 · AP2 · AR1 · AS1 · AT1 · AU1 · AY1 · B2 · B3 · B12 · B17  · B21 · BF1 · BU1 · C1 · D13 · D14 · D16 · D18 · F1 · H1 · H2 · H6 · H14 · H15 · I1 · J2 · K1 · K2 · K3 · K4 · L1 · L2 · M1 · M3 · M8 · M9 · M10 · M11  · P2 · P3 · R1 · T1 · T2 · T3 · U1 · V1 · W2 Family 6 A2 · B1 · B2 · B3 · C1 · C2 · C3 · C4 · C6 · C65 · C68 · C70 · C74 · C75 · C76 · F1 · J1 · K2 · K3 · K6 · M1 · N1 · N2 · P1 · Q1 · S1 · T1 · V1 · X1 · Y1 Family 7 A2 · A5 · A10 · A17 · C1 · C2 · D2 · D4 · E24 · G1 · G2 · G3 Family 8 A1 · B2 · B3 · B4 · B8 · B12 · D1 · D2 · D4 · G1 · G2 · G5 · H1 · H2 · H3 · I2 · J1 · J3 · K1 · K3 · K5 · S1 · U1 Family 9 A2 · A4 · G1 · G4 · I1 · K2 · Q1 · Q2 Family 10 A2 · A3 · A4 · A5 · A6 · A7 · AD1 · AG1 · C1 · D4 · G2 · G3 · G4 · G6 · G7 · G8 · G9 · H1 · H2 · H3 · H4 · H5 · J1 · J3 · J5 · J6 · K1 · K2 · P1 · Q1 · R2 · S1 · T2 · V1 · W1 · X1 · Z1 Family 11 A1 · G2 · H1 · H4 · H6 · L1 Family 12 D2 · D3 Family 13 A1 · C2 · C3 · C4 · C5 · C8 · C9 · D1 · F1 · G1 · H1 · J1